Clinical observation on the termination of early pregnancy by compound Mifepristone combined with Misoprostol

Objective To observe the curative effect and safety of compound mifepristone combined with misoprostol on the termination of early pregnancy.Methods 151 women who ask for termination of early pregnancy were randomly divided into two groups,observation group taking compound Mifepristone combined with Misoprostol,while control group taking Mifepristone combined with Misoprostol.Results The complete abortion rate in the observation group were higher than that of the control group(96.0% vs 89. 5%),and the failure rate in the observation group were lower than that of the control group(1.3% vs 3.9%),the time of gestational sac discharge in the observation group were shorter than in the control group[(3.7±1.2)h vs (4.1±1.5)h],but there were no obvious difference between these two groups(P0.05).The time of bleeding post-abortion in the observation group were significantly shorter than in the control group[(12.3±3. 6)h vs (17.1±4.7)h] (P0.01). There were no significant difference on the rate of side effects between these two groups(P0.05).Conclusions Compound Mifepristone combined with Misoprostol is effective on the termination of early pregnancy with small bleeding post-abortion.