Preliminary studies on the genetic variation in Oncomelania hupensis from different schistosomiasis-endemic areas in Anhui Province

Objective To explore the genetic variation in Oncomelania hupensis from different schistosomiasis-endemic areas in Anhui Province.Methods Snails were collected from 2 different areas in Ningguo and Wuhu.The genomic DNA extracted from the adults of O.hupensis were amplified by random amplified polymorphic DNA(RAPD)with seven random primers,and the genetic distance was measured according to the results obtained from the agarose gel electrophoresis analysis.Results The RAPD products were polymorphic,and there were some discrepancies in the numbers and size of the amplified DNA fragments.Except for the common fragments,their distinctive fragments suggested the diversity among Ningguo and Wuhu isolates.The genetic distance between Ningguo and Wuhu isolates was 0.387.Conclusion There is genetic variation in Oncomelania hupensis from different schistosomiasis-endemic areas in Anhui Province.