Genitourinary mycoplasma infection and drug sensitivity of patients in Shandong

Objectives: To investigate the infection of genitourinary mycoplasma and drug sensitivity of the patients in Shandong.Methods: we selected 3550 suspected genitourinary infection patients from both outpatients and inpatients from 7 hospitals in Jinan and Weifang.By using mycoplasma cultural method,we tested urea mycoplasma(Uu) and mycoplasma hominis(Mh) in the genitourinary secretion of the patients.We detected drug sensitivity to 12 kinds of antibiotics with drug sensitivity kits.Results: 780 cases were positive with positive rate 21.97%.Among the positive,cases of pure urea mycoplasma infection were 653(83.72%);cases of pure mycoplasma hominis were 40(5.13%);and both Uu and Mh were 87 cases(11.15%).In recent years,the mycoplasma infection has been gradually declining.Urea mycoplasma is sensitive to tetracycline,doxycycline and josamycin,clarithromycin and minocycline,while mycoplasma hominis is less sensitive to clarithromycin.The mixture of urea mycoplasma(Uu) and mycoplasma hominis(Mh) has resistance to clarithromycin.Conclusion: the causes of genitourinary infection are urea mycoplasma.The mixture of urea mycoplasma(Uu) and mycoplasma hominis(Mh) improves resistance to clarithromycin.The choice drugs to treat mycoplasma infection are doxycycline,josamycin and minocycline.