Clinical Research about Edaravone in Acute Cerebral Infarction

Objective To evaluate the efficacy and adverse reactions of Edaravone in the treatment of acute cerebral infarction(ACI).Methods A randomized controlled study on 60 patients with ACI.They were allocated into treatment group(n= 30) and control group(n= 30).Patients in both groups were given regular treatment.Patients in treatment group also received Edaravone injection 30 mg twice per day for 14 days.Then eurological deficits of patients in both groups were assessed by NIHSS respectively before and after the treatment.Clinical efficacy was evaluated according to changes NIHSSscores on the14d.Results There was a significant difference NIHSS between treatment group and controlgroup(P0.05).There was no distinct adverse reaction seen in these two groups.Conclusion Edaravone can improve impaired neurological function and activities of daily living in patients with acute cerebral infarction without obviously adverse reaction.Edaravone is effective and safe in the treatment of patients with acute cerebral infarction.It is worthy to be recommen