Effect Observation of Edaravone as Treatment of Acute Cerebral Infarction

Objective To evaluate the effectiveness and safety of edaravone injection in the treatment of acute cerebral infarction.Methods A randomized,double-blind,controlled trial was adopted.156 patients with acute cerebral infarction onset within 72 hours were randomized into edaravone group(n=78)and control group(n=78).Cases in treatment group were treated with edaravone intravenous drip of 30mg,twice a day for 14 days,along with salvia miltiorrhiza 20 mL/d and oral taken aspirin 100 mg as basic treatment.The control group was limited to the basic treatment.Neurological deficit score(NIHSS)and assessment of daily living(ADL)of patients before and after treatment for 14 days were assessed to evaluate the therapy.Results After 14 days of treatment,in the treatment group and the control group NIHSS decrease scores were(16.42±2.13)and(12.23±2.16)points,significant difference between the two groups(P0.05).ADL score increase of the two groups were(35.23±32.2)and(23.2±23.5)respectively,significant difference between the two groups(P0.05).Conclusion Edaravone can improve neurological deficit of acute cerebral infarction,which is safe and effective and should be widely applied.