Distribution and drug of susceptibility of the common pathogens in urinary system infection.

Objective To analyze the distribution of common pathogens in urinary system infection and the their drug sensitivity in order to provide a scientific basis for clinical diagnosis and rational use of antibiotics.Methods The results of the distribution and drug sensitivity for 239 pathogens strains isolated from the urine specimens in our hospital between January 2008 and September 2009 were retrospectively analyzed.Results The Gram-negative bacilli infection rate was 57.7%.The fungus infection rate was 22.2%.The Gram-Positive bacteria infection rate was 20.1%.The top three pathogens were Escherichia coli (33.1%), Candida albicans (10.5%) and Enterococcus faecalis (9.3% ).The Gram-negative bacilli have extremely sensitivity to the carbapenem except for Acinetobacter baumannii.The sensitivity of Gram-Positive bacteria to vancomycin, linezolid and teicoplanin was 100%.Extended-Spectrum beta-lactamase (ESBLs)-producing bacteria and Methicillin-resistant Staphylococcus aureus(MRSA) had high occurrence.Conclusion Gram-negative bacilli were the most common pathogens collected from the patients with urinary system infection.There were high resistant rates to common antibiotic.The rate of fungus infection in urinary system was higher than the rate of Gram-Positive bacteria infection.It is critical to know the distribution and antibiotic resistance of pathogens for the reasonable use of antibiotics.