2013•Chinese Journal of Clinical Rational Drug UseRequires access

Curative Effect Observation with Different Dosage Form of Methylcobalamin in the Treatment of Diabetic Peripheral Neuropathy

Xu We

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Abstract

Objective To probe into the therapeutic effectiveness of methylcobalamin administered by different dosage form in patients with diabetes peripheral neuropathy. Methods 67 cases of diabetic peripheral neuropathy patients were randomly divided into two groups,A group of 32 cases,giving methylcobalamin 0.5 mg,im,Qd;B group 35 examples,giving methylcobalamin piece of 0.5 mg,Po,Tid,the period of treatment lasted 2 weeks.Then evaluate respectively on the nerve symptoms and symptom score(TSS) before and after 2 weeks. Results Compared with before treatment,the nerve symptoms and TSS score of two groups are improved significantly after treatment,and the group A is better than that of group B. Conclusion Methylcobalamin can effectively improve diabetes peripheral neuropathy,and intramuscular injection group is better than that of oral medicine group.

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What this paper is about

Objective To probe into the therapeutic effectiveness of methylcobalamin administered by different dosage form in patients with diabetes peripheral neuropathy. Methods 67 cases of diabetic peripheral neuropathy patients were randomly divided into two groups,A group of 32 cases,giving methylcobalamin 0.5 mg,im,Qd;B group 35 examples,giving methylcobalamin piece of 0.5 mg,Po,Tid,the period of treatment lasted 2 weeks.Then evaluate respectively on the nerve symptoms and symptom score(TSS) before and after 2 weeks. Results Compared with before treatment,the nerve symptoms and TSS score of two groups are improved significantly after treatment,and the group A is better than that of group B. Conclusion Methylcobalamin can effectively improve diabetes peripheral neuropathy,and intramuscular injection group is better than that of oral medicine group.

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Available abstract

Objective To probe into the therapeutic effectiveness of methylcobalamin administered by different dosage form in patients with diabetes peripheral neuropathy. Methods 67 cases of diabetic peripheral neuropathy patients were randomly divided into two groups,A group of 32 cases,giving methylcobalamin 0.5 mg,im,Qd;B group 35 examples,giving methylcobalamin piece of 0.5 mg,Po,Tid,the period of treatment lasted 2 weeks.Then evaluate respectively on the nerve symptoms and symptom score(TSS) before and after 2 weeks. Results Compared with before treatment,the nerve symptoms and TSS score of two groups are improved significantly after treatment,and the group A is better than that of group B. Conclusion Methylcobalamin can effectively improve diabetes peripheral neuropathy,and intramuscular injection group is better than that of oral medicine group.

Key concepts: Methylcobalamin, Medicine, Peripheral neuropathy, Peripheral, Intramuscular injection, Diabetes mellitus, Internal medicine, Surgery

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Curative Effect Observation with Different Dosage Form of Methylcobalamin in the Treatment of Diabetic Peripheral Neuropathy — Research Paper | ScholarLens