Clinical Research on Damages of Morning Blood Pressure Surge of Hypertension on Cardiovascular Structures and Renal Functions.

Objective To investigate the damages of morning blood pressure surge(MBPS) of hypertension patients on the cardiovascular structures and renal functions.Methods 164 patients were divided into MBPS group(n=65) and non-MBPS group(n=99) according to 24h ambulatory blood pressure monitoring.Body mass index(BMI) and left ventricular mass index(LVMI)were calculated,serum lipids profile,fasting blood glucose,creatinine,urinary microalbumin,α1-microglobulin,urinary β2–microglobulin were examined.Results 24-hour,day and night systolic blood pressure and diastolic blood pressure in MBPS group were significantly higher than those in non-MBPS group(P0.05).LVMI,urinary microalbumin,α1-microglobulin,urinary β2–microglobulin in MBPS group were higher than those in non-MBPS group(P0.05).Conclusion The hypertension patients with MBPS were tended to suffer more damage of cardiac structures and renal functions.