Comparison of effects of mifepristone and levonorgestrel on emergency contraception

Objective: To compare the effects of mifepristone and levonorgestrel on emergency contraception.Methods: 206 patients with no protective sex required emergency contraception within 72 h were randomly divided into group1(n=136) and group 2(n=70).In group 1,single oral mifepristone 25 mg;in group 2,oral levonorgestrel 0.75 mg and once more 0.75 mg after 12 h.Results: There were two cases of pregnancy in group 1 and three cases of pregnancy in group 2,the rate of failure was 1.47% in group 1 and 4.29% in group 2,the rate of effective contraception was 84.10% in group 1 and 61.34% in group 2,the rate of side reaction was 7.53% in group 1 and 17.14% in group 2.Conclusion: Both mifepristone and levonorgestrel are effective emergency contraceptives,but mifepristone for emergency contraception is better than levonorgestrel.