Assessment of microwave combined with 5% imiquimod cream and recombinant human interleukin-2 in the treatment of condyloma acuminatum

Objective:To determine the relapse of the recombinant human interleukin-2 in the treatment of condyloma acuminatum(CA).Methods:One hundred and eight patients with CA were divided into control group(65 cases) and treatment group(43 cases).The warts in both treatment group and control group were removed by microwave,and then,5%imiquimod cream was applied on the lesions.Apart from these,recombinant human interleukin-2,0.2 million units every other day for 15 times,was injected intramuscularly for the patients in the treatment group.The relapse rates between the two groups were compared at month 6 after the treatment.Results:The number of relapsed patients was 2(3.08%) and 9 cases(20.93%),with a significant difference between the two groups(P0.01).Conclusion:Microwave combined with topical 5%imiquimod cream and intramuscular injection of recombinant human interleukin-2 can reduce recurrent rate of CA.