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Antibacterial constituents from the flowers of Trollius chinensis Bunge

Huiming Hua

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Abstract

Objective To study the antibacterial constituents from the water extract of the flowers of Trollius chinensis Bunge.Methods The constituents were isolated by repeated column chromatography on silica gel and Sephadex LH-20 and identified by physico-chemical characteristics and spectroscopic analysis.Results Seven compounds were isolated from the CHCl3 and ethyl acetate extracts,which were identified as:veratic acid(1),benzoic acid(2),(R)-10,16-dihydroxyhexadecanoic acid(3),apigenin(4),luteolin(5),salvigenin(6),and quercetin(7).Conclusions Compounds 24 are isolated from this genus for the first time.

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What this paper is about

Objective To study the antibacterial constituents from the water extract of the flowers of Trollius chinensis Bunge.Methods The constituents were isolated by repeated column chromatography on silica gel and Sephadex LH-20 and identified by physico-chemical characteristics and spectroscopic analysis.Results Seven compounds were isolated from the CHCl3 and ethyl acetate extracts,which were identified as:veratic acid(1),benzoic acid(2),(R)-10,16-dihydroxyhexadecanoic acid(3),apigenin(4),luteolin(5),salvigenin(6),and quercetin(7).Conclusions Compounds 24 are isolated from this genus for the first time.

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Available abstract

Objective To study the antibacterial constituents from the water extract of the flowers of Trollius chinensis Bunge.Methods The constituents were isolated by repeated column chromatography on silica gel and Sephadex LH-20 and identified by physico-chemical characteristics and spectroscopic analysis.Results Seven compounds were isolated from the CHCl3 and ethyl acetate extracts,which were identified as:veratic acid(1),benzoic acid(2),(R)-10,16-dihydroxyhexadecanoic acid(3),apigenin(4),luteolin(5),salvigenin(6),and quercetin(7).Conclusions Compounds 24 are isolated from this genus for the first time.

Key concepts: Apigenin, Luteolin, Chemistry, Column chromatography, Sephadex, Silica gel, Antibacterial activity, Benzoic acid

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