Optimization of ultrasonic-microwave synergistic extraction of grape seed oil by response surface methodology

The effects of different extractants,solvent to material ratio,extraction time and microwave power on extraction yield of grape seed oil were investigated.Then the ultrasonic-microwave synergistic extraction(UMSE)parameters of grape seed oil were optimized by response surface methodology.At last,the effects of UMSE and other extraction techniques were compared.The result showed that the ultrasonic-microwave synergistic extraction parameters were solvent(ethyl acetate)to material ratio 10mL/g,extraction time 121s,microwave power 187W and the extraction yield(EY)was up to31.885% under this extraction condition.Compared with other extraction techniques,UMSE had a higher extraction yield and a shorter extraction time.