The Effect of 0.05% Desonide Cream Combined with 0.025% Tretinoin Cream on Hand Eczema

Objective This experiment aims to study the clinical efficacy and safety of using 0.05% Desonide cream combined with 0.025% Tretinoin cream on hand eczema(HE).Methods There were 124 subjects with hand eczema in this experiment,they were randomly divided into the treatment group and the control group.The treatment group used 0.05% Desonide cream combined with 0.025% Tretinoin cream on their hands.The control group used Hydrocortisone butyrate combined with 0.025% Tretinoin cream on their hands.The treatment lasted for two weeks.Results After the two-week treatment,the therapeutic indexes have sharply dropped.The cure rates and the effective rates of the treatment group were 67.19% and 90.63% respectively,while those of the control group were 48.33% and 71.67%.There were no serious side-effects.Conclusions The cure rates of using 0.05% Desonide cream combined with 0.025% Tretinoin cream on hand eczema are high and the rates of adverse reactions are low.Therefore,it is a safe and effective treatment method.