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2008•The Journal of Clinical PsychiatryRequires access

Control study of escitalopram and maprotiline in treatment of depression

Zhang Hua-bia

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Abstract

Objective:To detect the efficacy and side effects of escitalopram in the treatment of depresssion.Method:63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks.Hamilton depressive scale(HAMD),clinical global impression severity of illness(CGI-SI)and treatment emergant symptom scale(TESS)were used to evaluate the efficacy and side effects before and after the treatment.Results:There was no significant difference in the efficacy between these two groups.Escitalopram took effect more quickly and less side effects than maprotiline.Conclusion:Escitalopram is a safe and effective antidepressant.

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What this paper is about

Objective:To detect the efficacy and side effects of escitalopram in the treatment of depresssion.Method:63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks.Hamilton depressive scale(HAMD),clinical global impression severity of illness(CGI-SI)and treatment emergant symptom scale(TESS)were used to evaluate the efficacy and side effects before and after the treatment.Results:There was no significant difference in the efficacy between these two groups.Escitalopram took effect more quickly and less side effects than maprotiline.Conclusion:Escitalopram is a safe and effective antidepressant.

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Available abstract

Objective:To detect the efficacy and side effects of escitalopram in the treatment of depresssion.Method:63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks.Hamilton depressive scale(HAMD),clinical global impression severity of illness(CGI-SI)and treatment emergant symptom scale(TESS)were used to evaluate the efficacy and side effects before and after the treatment.Results:There was no significant difference in the efficacy between these two groups.Escitalopram took effect more quickly and less side effects than maprotiline.Conclusion:Escitalopram is a safe and effective antidepressant.

Key concepts: Escitalopram, Maprotiline, Hamd, Clinical Global Impression, Antidepressant, Depression (economics), Hamilton depression scale, Psychology

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