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2010•Medical Journal of Chinese People's HealthRequires access

A control study on escitalopram and paroxetine in the treatment of depression

Zhang Wen-shun

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Abstract

Objective:To compare efficacy and side effects between escitalopram and paroxetine in the treatment of depression.Methods:84 inpatients and outpatients with a diagnosis of depression according to CCMD-3 were involved in this study,they were randomly assigned to escitalopram group(n = 42) and paroxetine group(n = 42) for 8weeks.Effects and side reactions were evaluated with HAMD,HAMA,CGI-SI and TESS before and after the treatment.Results: Findings indicated that efficacy of escitalopram was similar to than of paroxetine,however escitalopram took effect more quickly and its side effects were less than paroxetine.Conclusions: Escitalopram is an effective and safe antidepressant.It is suggested that escitalopram could be used as a first-line antidepressant in the treatment of depression.

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What this paper is about

Objective:To compare efficacy and side effects between escitalopram and paroxetine in the treatment of depression.Methods:84 inpatients and outpatients with a diagnosis of depression according to CCMD-3 were involved in this study,they were randomly assigned to escitalopram group(n = 42) and paroxetine group(n = 42) for 8weeks.Effects and side reactions were evaluated with HAMD,HAMA,CGI-SI and TESS before and after the treatment.Results: Findings indicated that efficacy of escitalopram was similar to than of paroxetine,however escitalopram took effect more quickly and its side effects were less than paroxetine.Conclusions: Escitalopram is an effective and safe antidepressant.It is suggested that escitalopram could be used as a first-line antidepressant in the treatment of depression.

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Available abstract

Objective:To compare efficacy and side effects between escitalopram and paroxetine in the treatment of depression.Methods:84 inpatients and outpatients with a diagnosis of depression according to CCMD-3 were involved in this study,they were randomly assigned to escitalopram group(n = 42) and paroxetine group(n = 42) for 8weeks.Effects and side reactions were evaluated with HAMD,HAMA,CGI-SI and TESS before and after the treatment.Results: Findings indicated that efficacy of escitalopram was similar to than of paroxetine,however escitalopram took effect more quickly and its side effects were less than paroxetine.Conclusions: Escitalopram is an effective and safe antidepressant.It is suggested that escitalopram could be used as a first-line antidepressant in the treatment of depression.

Key concepts: Escitalopram, Paroxetine, Antidepressant, Depression (economics), Hamd, Citalopram, Psychiatry, Psychology

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