Effect of Rosuvastatin and Atorvastatin on lipid,hs-CRP and restenosis after coronary stenting of patients with acute coronary syndrome

Objective To observe the effect of Rosuvastatin and Atorvastatin on blood lipid,CRP and restenosis after coronary stenting of patients with acute coronary syndrome.Methods One hundred and eleven patients with acute coronary syndrome after PCI were randomly divided into Rosuvastatin group(Rosuvastatin 20 mg+routine treatment) and Atorvastatin group(Atorvastatin 40 mg+routine treatment).Before and after operation for 6 months,TC,TG,LDL-C,HDL-C and hs-CRP were detected,the coronarography was rechecked,the rate of restenosis was measured,the incidence of angina was recorded,and the differences of the two groups were compared.Results TC,TG,LDL-C,hs-CRP and the incidence of angina in Rosuvastatin group were all lower than those in Atorvastatin group(P 0.05),while HDL-C was higher than that in Atorvastatin group.But there was no statistically significant difference of the incidence of restenosis between the two groups(P 0.05).Conclusion Rosuvastatin has stronger effects in regulating lipid,anti-inflammation and lowering incidence of angina than Atorvastatin.