2008Unpublished venueRequires access

The Research of RNAi and its Application

LI Mei-hong

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Abstract

RNAi(RNA interference) is a mechanism which is the after transcription Gene Silence triggered by double-strand RNA.RNAi has a contribution that can interfere with advanced activities of the cell via regulation and turn off gene expression.This mechanism is found ubiquitous in eukaryote and plays a role of resisting inbreak of virus and restraining the activity of transposon.The research of RNAi has achieved a great number of results,that may provide a new strategy for gene therapy of cancer.

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What this paper is about

RNAi(RNA interference) is a mechanism which is the after transcription Gene Silence triggered by double-strand RNA.RNAi has a contribution that can interfere with advanced activities of the cell via regulation and turn off gene expression.This mechanism is found ubiquitous in eukaryote and plays a role of resisting inbreak of virus and restraining the activity of transposon.The research of RNAi has achieved a great number of results,that may provide a new strategy for gene therapy of cancer.

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Key contribution

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Available abstract

RNAi(RNA interference) is a mechanism which is the after transcription Gene Silence triggered by double-strand RNA.RNAi has a contribution that can interfere with advanced activities of the cell via regulation and turn off gene expression.This mechanism is found ubiquitous in eukaryote and plays a role of resisting inbreak of virus and restraining the activity of transposon.The research of RNAi has achieved a great number of results,that may provide a new strategy for gene therapy of cancer.

Key concepts: RNA interference, Transposable element, Gene, Biology, Mechanism (biology), Transcription (linguistics), Gene expression, Eukaryote

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