A Study on Technology for Extraction of Pearl Drop pills

Objective: To optimize extraction technology of Pearl Drop pill.Methods: Orthogonal experiments were carried out,using 3,4-O-dicaffeoyl-quinic acid and glycyrrhizic acid as evaluation indexes to develop a suitable extraction technology through studying imbitition amount,decoction duration,decoction times,and concentration of alcohol precipitation.Results: The optimal water extration condition was as follows: decocting the drug for three times in tenfold volume of water,1 hour for each time.The optimal alcohol precipitation extraction condition was as follows: the relative density of drug liquid be adjusted to 1.08,the concentration of alcohol precipitation kept 60%,and stored for 12 hours.Conclusions: This extraction technique is reasonable,feasible,and provids a scientific basis for industrial production.