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Observation of the Therapeautic Effect of Cephathiamidine Combined with Ambroxol Treatment Community-acquired Pneumonia 158 cases

Pin Zhang

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Abstract

Objective To observe the therapeutic effect of cephathiamidine combined with ambroxol treatment community-acquired pneumonia(CAP) of children.Methods 314 CAP cases were randomly divided into treatment group(158 cases) and control group(156 cases),the two groups were both given supporting treatments such as keeping airway open,sucking phlegm,oxygen and atomization etc.,based on which,the treatment group was given cefathiamidine 50 mg/kg,and ambroxol 7.5 mg/kg at the same time.And for the control group based on conventional treatment,cefazolin injection 50 mg/kg was given.Fever,cough,shortness of breath,pulmonary fine wet rales disappearance,chest x-ray inflammation absorption etc.of the children in two groups during the administration were observed.Results The total effective rate of the treatment group was 94.9%,the total effective rate of the control group was 61.6%,the difference was statistically significant(P0.05).The clinical symptoms of the treatment group were obviously improved with significant difference to the control group(P0.05).Bacterial negative conversion rate in treatment group Staphylococcus aureus,escherichia coli,pneumococcal infections,was obviously higher than the control group,there was significant difference between two groups(P0.05).Conclusion Cefathiamidine and ambroxol combined treatment for pneumonia,has good synergy effect,making it an effective treatment for CAP,worthy of popularization.

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Objective To observe the therapeutic effect of cephathiamidine combined with ambroxol treatment community-acquired pneumonia(CAP) of children.Methods 314 CAP cases were randomly divided into treatment group(158 cases) and control group(156 cases),the two groups were both given supporting treatments such as keeping airway open,sucking phlegm,oxygen and atomization etc.,based on which,the treatment group was given cefathiamidine 50 mg/kg,and ambroxol 7.5 mg/kg at the same time.And for the control group based on conventional treatment,cefazolin injection 50 mg/kg was given.Fever,cough,shortness of breath,pulmonary fine wet rales disappearance,chest x-ray inflammation absorption etc.of the children in two groups during the administration were observed.Results The total effective rate of the treatment group was 94.9%,the total effective rate of the control group was 61.6%,the difference was statistically significant(P0.05).The clinical symptoms of the treatment group were obviously improved with significant difference to the control group(P0.05).Bacterial negative conversion rate in treatment group Staphylococcus aureus,escherichia coli,pneumococcal infections,was obviously higher than the control group,there was significant difference between two groups(P0.05).Conclusion Cefathiamidine and ambroxol combined treatment for pneumonia,has good synergy effect,making it an effective treatment for CAP,worthy of popularization.

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Available abstract

Objective To observe the therapeutic effect of cephathiamidine combined with ambroxol treatment community-acquired pneumonia(CAP) of children.Methods 314 CAP cases were randomly divided into treatment group(158 cases) and control group(156 cases),the two groups were both given supporting treatments such as keeping airway open,sucking phlegm,oxygen and atomization etc.,based on which,the treatment group was given cefathiamidine 50 mg/kg,and ambroxol 7.5 mg/kg at the same time.And for the control group based on conventional treatment,cefazolin injection 50 mg/kg was given.Fever,cough,shortness of breath,pulmonary fine wet rales disappearance,chest x-ray inflammation absorption etc.of the children in two groups during the administration were observed.Results The total effective rate of the treatment group was 94.9%,the total effective rate of the control group was 61.6%,the difference was statistically significant(P0.05).The clinical symptoms of the treatment group were obviously improved with significant difference to the control group(P0.05).Bacterial negative conversion rate in treatment group Staphylococcus aureus,escherichia coli,pneumococcal infections,was obviously higher than the control group,there was significant difference between two groups(P0.05).Conclusion Cefathiamidine and ambroxol combined treatment for pneumonia,has good synergy effect,making it an effective treatment for CAP,worthy of popularization.

Key concepts: Ambroxol, Medicine, Phlegm, Therapeutic effect, Pneumonia, Significant difference, Anesthesia, Treatment and control groups

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