The application of The Low Dose Bupivacaine in Combined Spinal and Epidural Anesthesia to Cesarean Section.

Objective:To observe the efficacy and safety of 7.5g/L bupivacaine 1ml in combined spinal and epidural anesthesia (CSEA) for cesarean section.Methods:100 patients undergoing cesarean section were randomly devided into combined spinal and epidural with low dose bupivacaine (group A,n=50) and epidural anesthesia (group B,n=50).group A :7.5g/L bupivacaine 1mL for lumbar anesthesia,during operation when lumbar anesthesia was inadequate,16g/L lidocaine 5~10 mL was supplemented via epidural catheter.group B:16g/L lidocaine 10~15 mL for epidural anesthesia.Sensory block time,beginning time of operation,efficacy of analgesia and muscle relaxation were assayed.Blood pressure,heart rate and SpO 2 were gained before anesthesia,and 5、10、 30 min after the injection of the drug.And anesthesia complications were assayed. Results:The beginning time of effective anesthesia,the block time of the height and the beginning time of operation in group A were shorter than group B(P0.01); MAP and HR in group A decreased faster than group B(P0.01),Analgesia and muscle relaxation in group A were more satisfactory than group B. there was no significantly difference in anesthesia complications between the two groups(P0.05).Conclusion:Bupivacaine 7.5mg is effective and safe in CSEA for cesarean section with no increase in the complications.