Preparation of Molecularly Imprinted Polymer with 4-Aminoanyipyrine as Template and its Characteristics

Molecularly imprinted polymer with 4-Aminoanyipyrine as template was prepared by precipitation polymerization.Methacrylic acid was used as functional monomer and dodecanol/toluene was used as solvent.The effects of reaction conditions,including the volume of solvent,the concentration of functional monomer and crosslinker,on the characteristics of the molecularly imprinted polymer were investigated.The appropriate polymerization conditions occurrs when the molecular ratio of template to monomer to crosslinker is 1∶5∶20.The obtained polymer shows good specific recognition and binding capacity in the rebinding experiments,with the separation factor of 3.72.