2013•Journal of Tongji UniversityRequires access

Irbesartan in treatment of early type 2 diabetic nephropathy

Yang She-zhe

Abstract

Objective To observe clinical effects of Irbesartan in treatment of early type 2 diabetic nephropathy.Methods Ninety patients with early type 2 diabetic nephropathy were enrolled in the study,including 45 patients treated with conventional medication(control group) and another 45patients treated with irbesartan(observation group).The blood sugar,renal function index,urine albumin,plasma cystatin C were measured 3 months after treatment.Results Compare to control group,observation group had better clinical effect and laboratory results;there were significant differences in blood sugar(Glu,2hPG and HbAlc)and blood lipid(HDL-C,TG,LDL-C) levels,blood pressure control and kidney functions(U-mAlb and cystatin C) between two groups(all P 0.05).Conclusion Irbesartan has better clinical effect than conventional medication in treatment of early type 2 diabetic nephropathy.

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Key concepts: Irbesartan, Medicine, Diabetic nephropathy, Renal function, Urology, Cystatin C, Internal medicine, Type 2 diabetes