Significance of serum procalcitonin in acute onset of children asthma

Objective:To discuss the significance of serum procalcitonin(PCT)in antibiotics selection for acute onset of children asthma.Methods:342 children with acute asthma were randomly divided into antibiotic group and control group which were treated with antibiotics and without antibiotics separately.All the patients underwent PCT test and were marked as PCT-negative or PCT-positive.Compare the therapeutic effects of these two groups.Results:According to PCT test,89% patients got bacterial infection,all sever cases complicated with pneumonia in both groups were tested as PCT-positive(100%).After 3 days of treatment,there was no significant difference between the therapeutic effects of PCT-negative cases in both antibiotic group and the control(P0.05),while for the PCT-positive cases in the two groups,both the complete relief rate and the partial relief rate were significant different from each other.Conclusion:PCT test can help to differentiate bacterial infections from non-bacterial infections in acute onset of children asthma.