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2014•Anhui Medical and Pharmaceutical JournalRequires access

Clinical significance of procalcitonin measurement on use of antiotics of pneumonia in children

Zhu Guang-j

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Abstract

Objective To evaluate the value of serum procalcitonin( PCT) measurement on use of antibiotics of pneumonia in children. Methods 121 cases of pneumonia patients were randomly divided into two groups. Roche Cobas E411 chemiluminescence method was used to detect PCT. In experimental group,antibiotics was used while PCT ≥0. 25 μg·L-1,while PCT 0. 25 μg·L-1cases did not use antibiotics. In control group,antibiotics was used according to the conventional way. Efficacyes were compared after. Results Compared with the control group,the usage of antibiotic in Experimental group was lower significantly( P 0. 01). Conclusions There's a certain value of PCT measurement in distinguishing between bacterial and non-bacterial infection pneumonia and guiding the clinical use of antibiotics in children.

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What this paper is about

Objective To evaluate the value of serum procalcitonin( PCT) measurement on use of antibiotics of pneumonia in children. Methods 121 cases of pneumonia patients were randomly divided into two groups. Roche Cobas E411 chemiluminescence method was used to detect PCT. In experimental group,antibiotics was used while PCT ≥0. 25 μg·L-1,while PCT 0. 25 μg·L-1cases did not use antibiotics. In control group,antibiotics was used according to the conventional way. Efficacyes were compared after. Results Compared with the control group,the usage of antibiotic in Experimental group was lower significantly( P 0. 01). Conclusions There's a certain value of PCT measurement in distinguishing between bacterial and non-bacterial infection pneumonia and guiding the clinical use of antibiotics in children.

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Available abstract

Objective To evaluate the value of serum procalcitonin( PCT) measurement on use of antibiotics of pneumonia in children. Methods 121 cases of pneumonia patients were randomly divided into two groups. Roche Cobas E411 chemiluminescence method was used to detect PCT. In experimental group,antibiotics was used while PCT ≥0. 25 μg·L-1,while PCT 0. 25 μg·L-1cases did not use antibiotics. In control group,antibiotics was used according to the conventional way. Efficacyes were compared after. Results Compared with the control group,the usage of antibiotic in Experimental group was lower significantly( P 0. 01). Conclusions There's a certain value of PCT measurement in distinguishing between bacterial and non-bacterial infection pneumonia and guiding the clinical use of antibiotics in children.

Key concepts: Procalcitonin, Antibiotics, Pneumonia, Medicine, Bacterial pneumonia, Internal medicine, Gastroenterology, Microbiology

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