Characteristics of Coronary Lesions in Patients Older than 80 Years with Unstable Angina and Efficacy & Safety of Percutaneous Coronary Intervention

Objective To study the characteristics of coronary lesions in patients older than 80 years with unstable angina and to evaluate the efficacy and safety of percutaneous coronary intervention(PCI).Methods A total of 72 patients(elderly group,over 80 years old) and 187 patients(middle-aged group,40 to 60 years old) with unstable angina admitted to the cardiovascular center of the affiliated hospital of Beihua university from October 2008 to October 2011 were recruited in this study.All patients received PCI.The risk factors,Syntax scores of coronary lesions,distribution of coronary lesions segments,number and length of stent,short-term effectiveness,and complications were compared between the two groups.Results The prevalence of high blood pressure,diabetes,hyperlidemia,and smoking showed significant differences between the elderly group and middle-aged group(all P0.01).The coronary lesions of RCA and LCA took place in the 2nd-3rd segments and the 5th,11th,12th-13th segments respectively in the two groups.The differences in constituent ratio of coronary artery disease(CAD) counts,Syntax scores of coronary lesions,number and length of stent,hemorrhagic complications,incident rate of MACE were all significant(all P0.05).The significant differences were also found in the blood stream of target vessel TIMI 3 level,acute or sub-acute thrombosis,the incident rate of broke and mortality.Conclusion The coronary lesions in elderly patients had such characteristics as more numbers,more complex and more severity.The short-term efficacy and safety of PCI in treating elderly patients who had angina and pectoris but without severe brain,lung,kidney,valvular lesions were the same as those in middle-aged patients.