Clinical Effect of Diltiazem Combined Trimetazidine in Treatment of Unstable Angina

Objective To observe the clinic effect and safety of diltiazem combined trimetazidine in the treatment of unstable angina.Methods Forty six cases of unstable angina were randomly divided into two groups: control group and treatment group.The control group was given conventional nitrates,β-blockers,aspirin,clopidogrel and simvastatin;on the basis of these,treatment group was additionally given diltiazem and trimetazidine.The numbers of angina attacking,duration,ECG,blood pressure and heart rates were compared between the two groups.Results Compared with the control group,in the diltiazem combined trimetazidine treatment group,the number of angina attacking reduced,duration shortened(P0.05),ECG dropped significantly(P0.05);heart rates of both groups reduced,blood pressure dropped than that before the treatment(P0.05);after treatment,the heart rates,blood pressure was no significant difference between the two groups(P0.05).Conclusion Diltiazem combined trimetazidine has a good clinical efficacy and high safety in treatment of unstable angina.It is worthy of clinical application.