Study on pathogenic spectrum of respiratory tract infection and its drug susceptibility test in a hospital

Objective To investigate the distribution of the respiratory tract infection pathogenic spectrum and its drug susceptibility test,and to provide references for enhancing curative effect. Methods The distribution of respiratory tract infection and its drug susceptibility test of patients in Department of Respiratory Medicine from January 2013 to December 2014 in Shaanxi General Hospital of CAPF were retrospectively analyzed. Results Respiratory tract infection pathogens were widely distributed,mainly Gram negative bacilli(58. 71%). Among Gram negative bacilli,pseudomonas aeruginosa was the most,accounting for 26. 94%. The main drugs with the highest sensitivity to Staphylococcus aureus in respiratory tract infection were vancomycin( 100%),linezolid( 98. 94%),cotrimoxazole(78. 72%),levofloxacin(78. 72%). The main drugs with the highest sensitivity to Pseudomonas aeruginosa in respiratory tract infection were imipenem(79. 66%) and levofloxacin(71. 19%). The main drugs with the highest sensitivity to E. coli in respiratory tract infection were cotrimoxazole(88. 89%),levofloxacin( 83. 33%),piperacillin tazobactam( 77. 78%),amikacin( 72. 22%). Conclusion The Gram negative bacteria are the main bacteria in respiratory tract infection. The different drug resistances exist in different kinds of bacteria. Pathogens and antimicrobial susceptibility of bacteria should be understood well in the respiratory tract infection for reasonably selecting the drugs.