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Comparison of the Serum Biochemical Marks between Male and Female Nonalcoholic Fatty Liver Patients

Zhang Shui-shan

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Abstract

[Objective] To compare the differences of biochemical metabolism between male and female nonalcoholic fatty liver patients and explore preventive countermeasures.[Methods] Detection was made on the levels of TP,ALB,GLO,AST,ALT,TBIL,DBIL,IBIL,GLU,T CHO,TG,HDL C,LDL C,apoA1 and apoB 100 among 973 people who undertook physical examination; calculation was made on non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C, apoB 100/HDL C and TC/HDLC;comparison was made on the result between 59 nonalcoholic fatty liver patients and 202 healthy people in the control.[Results] The total morbidity of fatty liver was 9.05%,the rate of the male patients was 12.53%,which was significantly higher than that of the female ones(6.0%)(P0.05);significant difference was found among the 59 male patients in the levels of ALT,IBIL,TG,HDL C,LDL C,apoA1,non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C,apoB 100/HDL C and TC/HDLC(P0.05,P0.01);significant difference was also found among the 30 female patients in the levels of AST,TBIL,DBIL,IBIL,GLU,T CHO,TG,LDL C,apoA 1,non HDL C,and the ratios of apoB100/apoA1,LDL C/HD C,apoB 100/HDLC and TC/HDLC(P0.05, P0.01);non HDL C was obviously correlated with TC,LDLC,TG,HDLC,apoA1, apoB100,apoB100/apoA1 and TC/FIDLC(r=0.4113~0.9893,P0.01).[Conclusion] Metabolism disorder and liver damage are the common features of nonalcoholic fatty liver and there are significant differences between males and females;effective measure should be taken for the prevention and interference.

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What this paper is about

[Objective] To compare the differences of biochemical metabolism between male and female nonalcoholic fatty liver patients and explore preventive countermeasures.[Methods] Detection was made on the levels of TP,ALB,GLO,AST,ALT,TBIL,DBIL,IBIL,GLU,T CHO,TG,HDL C,LDL C,apoA1 and apoB 100 among 973 people who undertook physical examination; calculation was made on non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C, apoB 100/HDL C and TC/HDLC;comparison was made on the result between 59 nonalcoholic fatty liver patients and 202 healthy people in the control.[Results] The total morbidity of fatty liver was 9.05%,the rate of the male patients was 12.53%,which was significantly higher than that of the female ones(6.0%)(P0.05);significant difference was found among the 59 male patients in the levels of ALT,IBIL,TG,HDL C,LDL C,apoA1,non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C,apoB 100/HDL C and TC/HDLC(P0.05,P0.01);significant difference was also found among the 30 female patients in the levels of AST,TBIL,DBIL,IBIL,GLU,T CHO,TG,LDL C,apoA 1,non HDL C,and the ratios of apoB100/apoA1,LDL C/HD C,apoB 100/HDLC and TC/HDLC(P0.05, P0.01);non HDL C was obviously correlated with TC,LDLC,TG,HDLC,apoA1, apoB100,apoB100/apoA1 and TC/FIDLC(r=0.4113~0.9893,P0.01).[Conclusion] Metabolism disorder and liver damage are the common features of nonalcoholic fatty liver and there are significant differences between males and females;effective measure should be taken for the prevention and interference.

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Available abstract

[Objective] To compare the differences of biochemical metabolism between male and female nonalcoholic fatty liver patients and explore preventive countermeasures.[Methods] Detection was made on the levels of TP,ALB,GLO,AST,ALT,TBIL,DBIL,IBIL,GLU,T CHO,TG,HDL C,LDL C,apoA1 and apoB 100 among 973 people who undertook physical examination; calculation was made on non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C, apoB 100/HDL C and TC/HDLC;comparison was made on the result between 59 nonalcoholic fatty liver patients and 202 healthy people in the control.[Results] The total morbidity of fatty liver was 9.05%,the rate of the male patients was 12.53%,which was significantly higher than that of the female ones(6.0%)(P0.05);significant difference was found among the 59 male patients in the levels of ALT,IBIL,TG,HDL C,LDL C,apoA1,non HDL C and the ratio of apoB 100/apoA1,LDL C/HDL C,apoB 100/HDL C and TC/HDLC(P0.05,P0.01);significant difference was also found among the 30 female patients in the levels of AST,TBIL,DBIL,IBIL,GLU,T CHO,TG,LDL C,apoA 1,non HDL C,and the ratios of apoB100/apoA1,LDL C/HD C,apoB 100/HDLC and TC/HDLC(P0.05, P0.01);non HDL C was obviously correlated with TC,LDLC,TG,HDLC,apoA1, apoB100,apoB100/apoA1 and TC/FIDLC(r=0.4113~0.9893,P0.01).[Conclusion] Metabolism disorder and liver damage are the common features of nonalcoholic fatty liver and there are significant differences between males and females;effective measure should be taken for the prevention and interference.

Key concepts: Apolipoprotein B, Internal medicine, Apolipoprotein A1, Medicine, Endocrinology, Fatty liver, Lipid metabolism, Cholesterol

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