Relationship between N-terminal pro-brain natriuretic peptide and heart failure

Objective To investigate the relationship between plasma level of the N-terminal pro-brain natriuretic peptide(NT-ProBNP) and severity of heart failure.Methods Four hundred and forty-three patients with heart failure caused by organic heart disease(heart failure group) and 110 patients with non-organic heart disease hospitalized at the same time(control group) were selected.Electrochemiluminescence full-automatic immunity analyzer was used to determine the blood plasma NT-ProBNP level in the two groups,and the relationship between the NT-ProBNP level and heart failure and the cardiovascular event was evalnated.Results NT-ProBNP level of the heart failure group was obviously higher than that of the control group(P0.05),and the higher NYHA classification was,the NT-ProBNP level was higher(P0.05),the recurrent rate of cardiovascular events to be also higher.Conclusion NT-ProBNP has important position and value in the clinical diagnosis of heart failure,the cardiac function classification and prognostic evaluation,and can be used as a good index for monitoring heart function.