Clinical analysis of amiodarone in the treatment of 106 cases of senile congestive heart failure concomitant with ventricular arrhythmia

Objective To explore the effect and safety of amiodarone in the treatment of senile congestive heart failure(SCHF).Methods 106 cases of SCHF concomitant with ventricular arrhythmias patients caused by a variety of reasons were randomly divided into treatment group and control group according to hospitalized order.The two groups were treated with the same anti-CHF therapy,the treatment group was plused by amiodarone tablets with 0.2g,3 times/day,a week,further 0.2g,2 times/day,a week,later 0.1 to 0.2g,1 times/day to the end.The end of follow-up time was 24 months.Finally we analyzed the two groups in the anti-ventricular arrhythmias,left ventricular ejection fraction,sudden cardiac death,heart failure rehospitalization rates,adverse drug reactions,and so on.Results In treatment group,53 cases with low-dose amiodarone therapy can significantly increase the effectiveness of anti-arrhythmic,improve left ventricular ejection fraction and reduced the rate of sudden cardiac death and heart failure rehospitalization.The role of drug-induced arrhythmia and serious adverse reactions were lessen.Conclusion SCHF concomitant with ventricular arrhythmias treated with low-dose amiodarone has fewer side effects and obvious safety and is suited for the application of primary hospital.