2010•Journal of Medical ForumRequires access

Amiodarone in Treatment of Congestive Heart Failure with Ventricular Arrhythmia

Qinhua Xu

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Abstract

Objective To explore the efficacy and safety of Amiodarone in patients with congestive heart failure and ventricular arrhythmias.Methods Totally 160 cases of eligible congestive heart failure and ventricular arrhythmias were randomly divided into treatment group and control group,control group received conventional anti-heart failure therapy plus metoprolol,the treatment group was treated on the basis of routine additional amine ketone iodine,compared two groups of anti-arrhythmia,left ventricular ejection fraction,sudden cardiac death,heart failure readmission rates,adverse drug reactions and other aspects.Results The improvement in heart function and anti-arrhythmic efficacy of treatment group better than the control group,the readmission rate and mortality rate lower than the control group,the difference was significant(P0.05),the two groups was no difference in adverse events(P0.05).Conclusion Amiodarone in patients with congestive heart failure with ventricular arrhythmias is safe and effective,less adverse reactions.

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What this paper is about

Objective To explore the efficacy and safety of Amiodarone in patients with congestive heart failure and ventricular arrhythmias.Methods Totally 160 cases of eligible congestive heart failure and ventricular arrhythmias were randomly divided into treatment group and control group,control group received conventional anti-heart failure therapy plus metoprolol,the treatment group was treated on the basis of routine additional amine ketone iodine,compared two groups of anti-arrhythmia,left ventricular ejection fraction,sudden cardiac death,heart failure readmission rates,adverse drug reactions and other aspects.Results The improvement in heart function and anti-arrhythmic efficacy of treatment group better than the control group,the readmission rate and mortality rate lower than the control group,the difference was significant(P0.05),the two groups was no difference in adverse events(P0.05).Conclusion Amiodarone in patients with congestive heart failure with ventricular arrhythmias is safe and effective,less adverse reactions.

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Available abstract

Objective To explore the efficacy and safety of Amiodarone in patients with congestive heart failure and ventricular arrhythmias.Methods Totally 160 cases of eligible congestive heart failure and ventricular arrhythmias were randomly divided into treatment group and control group,control group received conventional anti-heart failure therapy plus metoprolol,the treatment group was treated on the basis of routine additional amine ketone iodine,compared two groups of anti-arrhythmia,left ventricular ejection fraction,sudden cardiac death,heart failure readmission rates,adverse drug reactions and other aspects.Results The improvement in heart function and anti-arrhythmic efficacy of treatment group better than the control group,the readmission rate and mortality rate lower than the control group,the difference was significant(P0.05),the two groups was no difference in adverse events(P0.05).Conclusion Amiodarone in patients with congestive heart failure with ventricular arrhythmias is safe and effective,less adverse reactions.

Key concepts: Heart failure, Medicine, Amiodarone, Cardiology, Internal medicine, Ejection fraction, Metoprolol, Adverse effect

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