Resistance analysis of Acinetobacter baumannii

Objective To investigate the antimicrobial resistance and drug- resistant spectrum characteristics of Acinetobacter baumannii clinical isolates. Methods Seventy strains of Acinetobacter baumannii were collected,and the K- B disk diffusion method were applied to analyze the antimicrobial resistance. Results Of all Acinetobacter baumannii strains,40 strains were multi- drug resistant( 57. 14%) and 6 strains were pan- drug resistant( 8. 57%). The antimicrobial resistant rates of Acinetobacter baumannii to imipenem, amikacin, meropenem and cefepime were 30. 00%,32. 86%,38. 57% and 41. 43%,respectively,which were lower than others. However,the antimicrobial resistant rates to other commonly used antibiotics were higher than 50. 00%. Conclusion The multi- drug resistance of Acinetobacter baumannii collected from the hospital was serious,and aba I gene played an important role in the multi- drug resistant mechanism of Acinetobacter baumannii.