Clinical Analysis and Therapy of Malassezia Folliculitis

Objective To investigate the curative effect of itraconazole and the complex lotion of ketoconazole.Methods One hundred and forty six patients with Malassezia folliculitis conformed by fungus examination were collected and divided into two groups.The treatment group treated by itraconazole(200 mg/d,per oral for 7 days) and complex lotion of ketoconazole(external application,tid,4 weeks),and the control group only by complex lotion of ketoconazole(external application,tid,4 weeks).Results The curative ratio and effective rate were 69.47% and 95.79% in the treatment group,35.29% and 82.35% in the control group respectively(P0.01).Conclusions The itraconazole per oral combine with complex lotion of ketoconazole external application is safe and effective for Malassezia folliculitis,and it can be generalized.