Simplified Method for Determination of Atrazine Residues in Corn and Soil Using QuEChERS and UPLC-MS/MS

A rapid method for the determination of atrazine residues in corn and soil was established based on matrix solid-phase dispersion and ultraperformance liquid chromatography-mass spectrometry(UPLC-MS/MS).The sample was extracted by acetonitrile and then purified by praimary secondary amine(PSA).The atrazine residues was analyzed by UPLC-MS/MS under multiple reaction monitoring mode.The qualitative results were obtained based on retention time, the precursor ion and two daughter ions, and the quantitation results were on the intension of the characteristic 216146 ion 、m/z 216174 ion and m/z 21696 ion. Average recoveries of atrazine in soil and corn samples were found in the range of 77.01%～112.62% at three spiking levels from 0.005 mg·kg-1 to 0.5 mg·kg-1 with relative standard deviations of 2.23%～8.43%. Limits of detections of atrazine were 0.39～0.91 μg·kg-1,while limits of quantifications were 1.33～3.02 μg·kg-1, respectively.The method is simple and suitable for the routine and confirmation analysis.