UPLC-MS/MS for simultaneous determination of three sulfonylurea herbicide residues in soil

A method detecting 3 herbicide residues including thifensulfuron-methyl,tribenuron methyl,chlorimuron-ethyl in soil was established by using QuEChERS-ultra-high performance liquid chromatographytandem mass spectrometry(UPLC-MS / MS).Soil samples were rapidly extracted by acetonitrile,purified by C 18 solid dispersant.The purified liquid was analysed by UPLC-MS / MS in multiple reaction monitoring(MRM) mode,and 0.1% formic acid in water and acetonitrile were used as mobile phase to complete gradient elution.The calibration curves of three herbicides have good linear correlation in the concentration range of 0.5 ~ 500 ng / mL(R = 0.996 ~ 0.999).The spike recovery experiments were carried out at levels of 10 μg / kg and 50 μg / kg,the average recoveries were between 81.4% and 92.9%,RSD were 5.5% ~ 10.6%,and the method detection limit(S / N = 3) were 0.12 ~ 0.16 μg / kg.The results showed that the method could be used for the detection of the actual soil samples.