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2007•The Journal of Medical Theory and PracticeRequires access

The Significance of Detection of Interleukin-15 in Serum From Patients with Chronic Hepatitis B

Tang Xianme

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Abstract

Objective: To investigate the law and significances of change of interleukin-15(IL-15) in serum from patients with chronic hepatitis B.Methods:The serum levels of IL-15 in patients with chronic hepatitis B(CHB) were measured by ELISA.Results:Concentrations of serum IL-15 in patients with different type of viral hepatitis were significantly higher than that in normal group(P0.01).The level of IL-15 in patients with severe hepatitis was the highest among those groups.According to the value of alanine aminotransferase(ALT),the serum IL-15 levels in the highest group were higher than that in other groups.The difference of the serum IL-15 levels was not significant between every two groups which were divided into on the concentration of HBV DNA.Conclusion:It is possible that IL-15 plays a role in liver inflammatory injury process.The detection of level of serum IL-15 is helpful to determination of the disease in patients with chronic hepatitis B.

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What this paper is about

Objective: To investigate the law and significances of change of interleukin-15(IL-15) in serum from patients with chronic hepatitis B.Methods:The serum levels of IL-15 in patients with chronic hepatitis B(CHB) were measured by ELISA.Results:Concentrations of serum IL-15 in patients with different type of viral hepatitis were significantly higher than that in normal group(P0.01).The level of IL-15 in patients with severe hepatitis was the highest among those groups.According to the value of alanine aminotransferase(ALT),the serum IL-15 levels in the highest group were higher than that in other groups.The difference of the serum IL-15 levels was not significant between every two groups which were divided into on the concentration of HBV DNA.Conclusion:It is possible that IL-15 plays a role in liver inflammatory injury process.The detection of level of serum IL-15 is helpful to determination of the disease in patients with chronic hepatitis B.

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Available abstract

Objective: To investigate the law and significances of change of interleukin-15(IL-15) in serum from patients with chronic hepatitis B.Methods:The serum levels of IL-15 in patients with chronic hepatitis B(CHB) were measured by ELISA.Results:Concentrations of serum IL-15 in patients with different type of viral hepatitis were significantly higher than that in normal group(P0.01).The level of IL-15 in patients with severe hepatitis was the highest among those groups.According to the value of alanine aminotransferase(ALT),the serum IL-15 levels in the highest group were higher than that in other groups.The difference of the serum IL-15 levels was not significant between every two groups which were divided into on the concentration of HBV DNA.Conclusion:It is possible that IL-15 plays a role in liver inflammatory injury process.The detection of level of serum IL-15 is helpful to determination of the disease in patients with chronic hepatitis B.

Key concepts: Medicine, Chronic hepatitis, Gastroenterology, Alanine aminotransferase, Internal medicine, Hepatitis B, Hepatitis, Significant difference

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