Relationship between serum IL-8、IL-10levels and liver lesion in patients with Viral hepatitis

The serum IL-8、IL-10 levels were determined in 76 patients with viral hepatitis by double-antibody sandwich ELISA.Results showed that the IL-8 levels in patients with any type of hepatits were higher significantly than normal persons;IL-8 levels in patients with chronic moderate and serious degree hepatitis was highest than others Serum IL-10 levels were increased sequentially in patients with chronic(moderate, serious degree)hepatitis、liver cirrhosis、severe hepatitis compared with normal control There was a positive correlation between serum IL-8 levels and SB、ALT. Our results suggested that IL-8 could reflect the degree of liver damage in patients with hepatitis, and Detecting IL-8 and IL-10 could predicting prognosis in patient with severe hepatitis,liver cirrhosis