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2007•Medical Journal of Chinese People's HealthRequires access

A clinical study of fluoxetine combined with psychotherapy in patients with post-stroke depression

Yan Ru-ling

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Abstract

Objective:To compare the curative effects of fluoxetine combined with psychotherapy and single fluoxetine in patients with post-stroke depression.Methods:126 patients with post-stroke depression were randomly divided into research group(n=66) treated with fluoxetine combined with psychotherapy and control group(n=60) treated with single fluoxetine for 6 weeks.The curative effects and side effects were evaluated with HAMD,SDS and TESS.Results: Two groups took effects at first weeked(P0.01),but the marked improvement rate of the reserch group was 87.8%,and the control group was 73.3%,which showed significant difference after 6 weeks treatment.The side effects of both groups were less.Conclusions: Fluoxetine is effective and safe in the treatment of patients with post-stroke depression,and psychotherapy is a good auxiliary method.

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What this paper is about

Objective:To compare the curative effects of fluoxetine combined with psychotherapy and single fluoxetine in patients with post-stroke depression.Methods:126 patients with post-stroke depression were randomly divided into research group(n=66) treated with fluoxetine combined with psychotherapy and control group(n=60) treated with single fluoxetine for 6 weeks.The curative effects and side effects were evaluated with HAMD,SDS and TESS.Results: Two groups took effects at first weeked(P0.01),but the marked improvement rate of the reserch group was 87.8%,and the control group was 73.3%,which showed significant difference after 6 weeks treatment.The side effects of both groups were less.Conclusions: Fluoxetine is effective and safe in the treatment of patients with post-stroke depression,and psychotherapy is a good auxiliary method.

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Available abstract

Objective:To compare the curative effects of fluoxetine combined with psychotherapy and single fluoxetine in patients with post-stroke depression.Methods:126 patients with post-stroke depression were randomly divided into research group(n=66) treated with fluoxetine combined with psychotherapy and control group(n=60) treated with single fluoxetine for 6 weeks.The curative effects and side effects were evaluated with HAMD,SDS and TESS.Results: Two groups took effects at first weeked(P0.01),but the marked improvement rate of the reserch group was 87.8%,and the control group was 73.3%,which showed significant difference after 6 weeks treatment.The side effects of both groups were less.Conclusions: Fluoxetine is effective and safe in the treatment of patients with post-stroke depression,and psychotherapy is a good auxiliary method.

Key concepts: Fluoxetine, Hamd, Post-stroke depression, Depression (economics), Significant difference, Stroke (engine), Medicine, Psychology

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