The spectrum and antimicrobial resistance of pathogens causing urinary tract infection

Objective To investigate the spectrum and antimicrobial resistance of pathogens causing urinary tract infection in adult.Method To analyze the spectrum and antimicrobial resistance of pathogens collected from urine cultures in hospitalized patients for urinary infections from January 1999 to October 2005.Results 160 positive cultures were isolated,Of them,157 were bacilli,3 were fungi.Gram-negative bacilli accounted for(77.8%,)with 51.3% of Escherrich's bacilli coli,gram-postive bacilli accounted for 20.6%.Resistance rates of Gram negative bacilli to amoxicillin,second generation cephlosporins,ceftazidime,imipenem,quinolones,aminoglycosides such as gentamicin,tobramycin and sulfanilamide were 85.9%,24.0%,12.5%,0.0%,57.6%,36.0% ～51.0% and(68.9)%.Conclusions E coli is still the major pathogen accountcd for urinany tract infection.Resistancc rates among common pathogens appear to be increasing to many common used agents.Drug-sensitivity test are needed to be taken into account when empirical therapy is used for urinary tract infection.