ScholarLens Back to search
2013•The Practical Journal of CancerRequires access

Clinicopathologic Analysis of 25 Cases of Dermatofibrosarcoma Protuberans

Peng Chu

Open publisher page 0 citations

Abstract

Objective To study the clinicopathological characteristics of dermatofibrosarcoma protuberans(DFSP).Methods Clinical pathological characteristics and immunohistochemical findings were observed in 25 cases of dermatofibrosarcoma protuberans.Results All cases of dermatofibrosarcoma protuberans(DFSP) were diagnosed by clinical characteristics、histopathologic characteristics、cell form and immunohistochemistry.Immunohistochemiscal staining showed that the tumor cells were positive for vimentin(100%、25/25),CD34(100%,25/25),Ki-67(60%,15/25),SMA(32%、8/25),actin(40%、10/25),while CD68、S-100、FⅧa and CK did not express.Conclusion DFSP is misdiagnosed easily.It is better for the diagnosis to find classical tissues structure and use immunohistochemistry.

About this research paper

What this paper is about

Objective To study the clinicopathological characteristics of dermatofibrosarcoma protuberans(DFSP).Methods Clinical pathological characteristics and immunohistochemical findings were observed in 25 cases of dermatofibrosarcoma protuberans.Results All cases of dermatofibrosarcoma protuberans(DFSP) were diagnosed by clinical characteristics、histopathologic characteristics、cell form and immunohistochemistry.Immunohistochemiscal staining showed that the tumor cells were positive for vimentin(100%、25/25),CD34(100%,25/25),Ki-67(60%,15/25),SMA(32%、8/25),actin(40%、10/25),while CD68、S-100、FⅧa and CK did not express.Conclusion DFSP is misdiagnosed easily.It is better for the diagnosis to find classical tissues structure and use immunohistochemistry.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To study the clinicopathological characteristics of dermatofibrosarcoma protuberans(DFSP).Methods Clinical pathological characteristics and immunohistochemical findings were observed in 25 cases of dermatofibrosarcoma protuberans.Results All cases of dermatofibrosarcoma protuberans(DFSP) were diagnosed by clinical characteristics、histopathologic characteristics、cell form and immunohistochemistry.Immunohistochemiscal staining showed that the tumor cells were positive for vimentin(100%、25/25),CD34(100%,25/25),Ki-67(60%,15/25),SMA(32%、8/25),actin(40%、10/25),while CD68、S-100、FⅧa and CK did not express.Conclusion DFSP is misdiagnosed easily.It is better for the diagnosis to find classical tissues structure and use immunohistochemistry.

Key concepts: Dermatofibrosarcoma protuberans, CD34, Immunohistochemistry, CD68, Vimentin, Dermatofibrosarcoma, Pathology, Pathological

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinicopathologic Analysis of 25 Cases of Dermatofibrosarcoma Protuberans — Research Paper | ScholarLens