Role of the therapeutic effect of buflomedil hydrochoride for injection in acute cerebral infarction

Objective To investigate the therapeutic effect of buflomedil hydiochoride for on jection inpro- gressive ischemic stroke.Methods 60 patients with cerebral infarction were divided into buflomedil hydrochoride for injection treatment group and control treatment.Then the nepal function deficits of patients were evaluated before and after 15 days.Serum MMP-9 levels in vein blood samples of ischemie stroke were detected.Results The inci- dence rate of progressive ischemic stroke in treatment group of buflomedil hydrochoride for injection was lower than that of control treatment group(P0.05).Serum MMP-9 levels were significantly improved in treatment group. Conclusion The treatment of buflomedil hydrochoride for injection could decrease the incidence of progressive is- chemic stroke.There might be a close relation between MMP-9 levels and ischemic stroke.