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2008•Journal of Chengdu University of Traditional Chinese MedicineRequires access

Effect of Toufengyu Drop Pill on Platelet Aggregation and Thrombosis

Leilei Huang

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Abstract

Separately based on platelet aggregation in rabbits induced by ADP,thrombosis hemiplegia in vivo induced by adrenaline-collagen in mice,observe the effect of Toufengyu drop pill on platelet aggregation and thrombosis.ResuLts:indicate that the all dosage groups of Toufengyu drop pill poss the inhibitory effects on platelet aggregation in rabbits induced by ADP;on thrombosis formation in vivo,high dose group significantly antagonize the thrombosis induced by a mixture of collagen and adrenaline,reduce the number of animal deaths and normalize hemiplegia.The effect may be one of the mechanism in the prevention of migraine.

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What this paper is about

Separately based on platelet aggregation in rabbits induced by ADP,thrombosis hemiplegia in vivo induced by adrenaline-collagen in mice,observe the effect of Toufengyu drop pill on platelet aggregation and thrombosis.ResuLts:indicate that the all dosage groups of Toufengyu drop pill poss the inhibitory effects on platelet aggregation in rabbits induced by ADP;on thrombosis formation in vivo,high dose group significantly antagonize the thrombosis induced by a mixture of collagen and adrenaline,reduce the number of animal deaths and normalize hemiplegia.The effect may be one of the mechanism in the prevention of migraine.

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Available abstract

Separately based on platelet aggregation in rabbits induced by ADP,thrombosis hemiplegia in vivo induced by adrenaline-collagen in mice,observe the effect of Toufengyu drop pill on platelet aggregation and thrombosis.ResuLts:indicate that the all dosage groups of Toufengyu drop pill poss the inhibitory effects on platelet aggregation in rabbits induced by ADP;on thrombosis formation in vivo,high dose group significantly antagonize the thrombosis induced by a mixture of collagen and adrenaline,reduce the number of animal deaths and normalize hemiplegia.The effect may be one of the mechanism in the prevention of migraine.

Key concepts: Thrombosis, In vivo, Platelet aggregation, Platelet, Pill, Medicine, Pharmacology, Bleeding time

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