Distribution of pathogens cultured from blood specimens and analysis of drug resistance

OBJECTIVE To investigate the distribution and characteristics of blood culture pathogens so as to provide basis for clinical medication.METHODS A retrospective analysis of the distribution and antibiotics resistance of pathogens isolated from blood culture was performed from Jan 2008 to Dec 2010.RESULTS A total of 579 strains of pathogens were isolated during the three years with the detection rate of 13.1%.The most common pathogenic bacteria were coagulase-negative Staphylococcus(169 strains,29.2%),Escherichia coli(105 strains,18.1%),Klebsiella pneumoniae(70 strains,12.1%) and Staphylococcus aureus(55 strains,9.5%).The gram-positive bacteria were highly susceptible to linezolid,teicoplanin,and vancomycin,and E.coli and K.pneumoniae were highly susceptible to imipenem.CONCLUSION It is of great significance in improving the cure rate to understand the blood culture result in a timely manner so as to provide basis for the clinical antibiotics therapy.