Application efficacy observation of statin intensive treatment in acute coronary syndrome patients after PCI surgery

Objective To explore the clinical efficacy of applying statin intensive treatment to acute coronary syndrome(ACS) patients after PCI surgery. Methods Eighty-eight ACS patients who underwent PCI surgery admitted into our hospital from November 2012 to November 2013 were selected as research objects and randomly divided into group A and group B.In the group A(n=40),patients were treated by regular therapy,while in the group B(n=48),statin intensive treatment was provided.The efficacy in both groups were observed. Results After treatment,the total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),and hypersensitive C reactive protein(hs-CRP) to some extent decreased in comparison with those before treatment in both groups.The decrease in the group B was more obvious with statistical differences(P0.05).The alanine transaminase(ALT) and creatinine(Cr) after treatment both increased,but didn′t display a significant difference between the two groups.The recurrent rate of angina pectoris and incidence of cardiac failure in the group A were 27.1% and 18.7%,while in the group B,they were 15.0% and 10.0% in turn,which were much lower than those in the group A and displayed statistical differences(P0.05). Conclusion Application of substantial amount of statins for intensive treatment in ACS patients after PCI surgery can obtain remarkable clinical effect and improve patient′s prognosis,which is worthy of expansion in clinic.