2014Asian Journal of Research in ChemistryRequires access

Validated UV- Spectroscopic estimation of Fenofibrate Concentration in Bulk and Dosage form

Ashok P. Pingale, Ghanshyam B. Jadhav, Amar Zalte, R.B. Saudagar

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Abstract

A simple, accurate, precise, sensitive and a highly selective ultra violet spectrophotometric method has been developed for the simultaneous estimation of in bulk and solid dosage form. The estimation of Fenofibrate was carried out at 286 nm. The developed method was validated for linearity, range, precision, recovery studies and interference study for mixture. All these parameters showed the adaptability of the method for the quality control analysis of the drug in bulk and in marketed formulations.

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What this paper is about

A simple, accurate, precise, sensitive and a highly selective ultra violet spectrophotometric method has been developed for the simultaneous estimation of in bulk and solid dosage form. The estimation of Fenofibrate was carried out at 286 nm. The developed method was validated for linearity, range, precision, recovery studies and interference study for mixture. All these parameters showed the adaptability of the method for the quality control analysis of the drug in bulk and in marketed formulations.

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Available abstract

A simple, accurate, precise, sensitive and a highly selective ultra violet spectrophotometric method has been developed for the simultaneous estimation of in bulk and solid dosage form. The estimation of Fenofibrate was carried out at 286 nm. The developed method was validated for linearity, range, precision, recovery studies and interference study for mixture. All these parameters showed the adaptability of the method for the quality control analysis of the drug in bulk and in marketed formulations.

Key concepts: Fenofibrate, Dosage form, Chromatography, Interference (communication), Linearity, Materials science, Chemistry, Biological system

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