2014•Asian Journal of Pharmaceutical AnalysisRequires access

Spectrophotometric Determination of and Validation of Zidovudine Concentration in Bulk and Dosage form

Ghanshyam B. Jadhav, Amar Zalte, R.B. Saudagar, Ashok P. Pingale

Abstract

A simple, accurate, precise, sensitive and a highly selective ultra violet spectrophotometric method has been developed for the simultaneous estimation of in bulk and solid dosage form. The estimation of Zidovudine was carried out at 266 nm. The developed method was validated for linearity, range, precision, recovery studies and interference study for mixture. All these parameters showed the adaptability of the method for the quality control analysis of the drug in bulk and in marketed formulations.

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Key concepts: Dosage form, Zidovudine, Materials science, Chromatography, Linearity, Biomedical engineering, Adaptability, Mathematics