Synthesis Phenyl Salicylate by Indirect Approach

In this paper,the phenyl salicylate was synthesized from salicylic acid,phenol in the presence of POCl3 with the yield of 95.71% and the purity of 98.5% by indirect approach.The optimum conditions were as follows: temperature was 80 ℃,the reaction time was 2.5 h,n(salicylic acid)∶ n(phenol) 1∶1.25,n(salicylic acid)∶ n(phosphorus oxychloride) 1∶0.58,which were achieved by the investigation of the reaction temperature,reaction time,reaction ratio.