2012Pesticide Research JournalRequires access

Synthesis and Nematicidal Activity of Pyrazole Derivatives

Archana Upadhyay, Madhuban Gopal, D. Prasad

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Abstract

A series of substituted chalcones and their corresponding pyrazoles were synthesized and evaluated for nematicidal activity in vitro against Meloidogyne incognita and Rotylenchulus reniformis. Few compounds viz. 1c, 3c, 5a and 5b showed good nematicidal activity when tested as EC formulations and can be identified as lead molecule for studying structure activity relationship and further modification.

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A series of substituted chalcones and their corresponding pyrazoles were synthesized and evaluated for nematicidal activity in vitro against Meloidogyne incognita and Rotylenchulus reniformis. Few compounds viz. 1c, 3c, 5a and 5b showed good nematicidal activity when tested as EC formulations and can be identified as lead molecule for studying structure activity relationship and further modification.

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Available abstract

A series of substituted chalcones and their corresponding pyrazoles were synthesized and evaluated for nematicidal activity in vitro against Meloidogyne incognita and Rotylenchulus reniformis. Few compounds viz. 1c, 3c, 5a and 5b showed good nematicidal activity when tested as EC formulations and can be identified as lead molecule for studying structure activity relationship and further modification.

Key concepts: Meloidogyne incognita, Rotylenchulus reniformis, Pyrazole, Terra incognita, In vitro, Molecule, Veterinary medicine, Nematode

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