Effect of substituents on the Fungitoxicity of 1,2,4-Oxadiazolines derived from 4-Methoxybenzalanilines
M.R. Manrao, Monika Jolly, Jyoti Sharma, P.S. Kalsi
Abstract
M.R. Manrao, Monika Jolly, Jyoti Sharma, P.S. Kalsi
Abstract
1,2,4-Oxadiazolines (IHa-IIId) with unsubstituted, 2-methyl, 2-thio and 2-hydroxy substituted N-phenyl ring were synthesized by the addition of benzonitrile oxide to 4-methoxybenzalanilines and its N-phenyl substituted derivatives (la-Id). The products were identified and confirmed on the basis of elemental analysis and spectral studies. These compounds were tested in vitro against Alternaria alternate, Curvularia lunata, Fusarium oxysporum, Stemphylium port and Helminthosporium maydis by spore germination iniibition methoho Compound IIId has been found to possess promising fungitoxicity against all the test fungi.
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1,2,4-Oxadiazolines (IHa-IIId) with unsubstituted, 2-methyl, 2-thio and 2-hydroxy substituted N-phenyl ring were synthesized by the addition of benzonitrile oxide to 4-methoxybenzalanilines and its N-phenyl substituted derivatives (la-Id). The products were identified and confirmed on the basis of elemental analysis and spectral studies. These compounds were tested in vitro against Alternaria alternate, Curvularia lunata, Fusarium oxysporum, Stemphylium port and Helminthosporium maydis by spore germination iniibition methoho Compound IIId has been found to possess promising fungitoxicity against all the test fungi.
Key concepts: Fusarium oxysporum, Curvularia, Alternaria, Spore germination, Germination, Biology, Veterinary medicine, Stereochemistry