Distribution and antibiotics resistance of pathogens in pediatric patients with pneumonia.

OBJECTIVE To explore distribution and drug resistance of pathogens isolated from children patients with pneumonia.METHODS The pathogenic bacteria isolated from sputum specimens of 598 children patients were identified and their drug resistance was analyzed.RESULTS Totally 272 isolates were detected in total 598 sputum specimens,including 201 strains of Gram-negative bacteria(73.9%),52 strains of Gram-positive bacteria(19.1%) and 19 strains of fungi(7.0%),and the isolating rate was 45.5%.Klebsiella pneumoniae and Escherichia coli were the main Gram-negative strains in which the detection rates of(extended-spectrum β-lactamases ESBLs) were 52.9% and 43.8%,respectively.The susceptibility of these isolates to imipenem and meropenem was the highest.Staphylococcus aureus was the main gram-positive bacterium and its highest susceptibility antibiotics were vancomycin and teicoplanin.CONCLUSION The Gram-negative bacteria are the main pathogens and different bacterial species show significant antibiotics resistance.As a result,analysis of distribution and drug resistance of pathogens is important for rational administration of antibiotics in clinic.